Continuous Eructations Treated by Emetine Hydrochloride
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Observations on the mechanism of emetine poisoning of myocardial tissue.
The effect of emetine hydrochloride on protein synthesis in rat myocardium was studied. Emetine inhibited incorporation of tritiated leucine into soluble proteins and actomyosin in an in vitro system using minced rat myocardium in a supporting medium. Fifty percent inhibition of incorporation of the isotope into soluble proteins and actomyosin occurred at an emetine concentration of 5 X 10~ M. ...
متن کاملEmetine hydrochloride and chloroquine in the treatment of children with amoebic liver abscess.
Although amoebic liver abscess is infrequent in children, the outcome is much less favourable than it is in adults. When treated with combined emetine hydrochloride, chloroquine, and aspiration, the prognosis is excellent in adults (Wilmot, 1962), this regime being more successful than treatment with a single drug (Wilmot, Powell, and Adams, 1959; Wilmot, Powell, MacLeod, and Elsdon-Dew, 1964)....
متن کاملA Note on Three Cases Treated with Emetine
S. L. M-, male, Mahomedan, aged 22. History of dysentery of five months' duration contracted in Bombay and for which he wns in a Bombay hospital for three months. He was given emetine hydrochloride i gr. hypodermically morning and evening for three days and this resulted in a gain of 3 lbs. in weight, the disappearance of blood and slime, the passage of a normal motion and a very great improvem...
متن کاملChildren with Amoebic Liver Abscess
A combination of emetine hydrochloride with chloroquine yields better results than either drug alone in the treatment of amoebic liver abscess in adults (Wilmot, Powell, and Adams, 1959). A similar combination of dehydroemetine with chloroquine is equally satisfactory (Wilmot, Powell, MacLeod, and Elsdon-Dew, 1964; Powell, Wilmot, MacLeod, and Elsdon-Dew, 1967). Dehydroemetine is claimed to be ...
متن کاملParesis Following Emetine Injections
sant action on the muscular and nervous systems, cases of actual paresis following injections of emetine hydrochloride are rare, and the following may be of interest. Case 1.?A Chinese lady had six hypodermic injections of emetine hydrochloride in the arm; after the third injection she developed increasing weakness in both upper extremities, and eventually could hardly lift up her hand or any-
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